Adlinameg 2.5/850mg Tablet | Anti-Diabetic | Medicine | ePharma
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Adlinameg 2.5/850mg Tablet

Generic: Linagliptin + metformin hydrochloride

Type: Tablet

Pack Size: 10 Pcs

(Linagliptin 2.5mg + Metformin Hydrochloride 850mg): A type 2 diabetes treatment for adults.


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Discount Price: ৳ 134.4
MRP: ৳ 140 4% Off

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✅ Description:

Adlinameg 2.5/850mg Tablet: Balancing Blood Sugar with Metformin and Linagliptin.

  • Type II diabetes mellitus, a chronic condition marked by high blood glucose levels, is managed with Adlinameg 2.5/850mg Tablet. This combination of Metformin and Linagliptin falls under the category of Antidiabetic agents. It's designed for adults whose sugar isn't adequately controlled by diet, exercise, and other medications.
  • This tablet works as an adjunct to diet and exercise, assisting in achieving better results. Type II diabetes arises from insufficient insulin (a hormone regulating glucose metabolism) production or decreased sensitivity of body cells to insulin.
  • Take Adlinameg 2.5/850mg Tablet with meals. Your blood sugar and kidney function will likely be monitored during treatment to prevent unwanted effects.
  • Notify your doctor about liver, kidney, or heart issues before taking Adlinameg 2.5/850mg Tablet. Also, inform them if you've experienced blood circulation problems or severe dehydration due to vomiting or diarrhea.
  • It's not suitable for severe uncontrollable diabetes, alcoholism, or severe systemic infections.
  • If pregnant or breastfeeding, consult your doctor before taking Adlinameg 2.5/850mg Tablet. Common side effects include nausea, diarrhea, stomach pain, constipation, loss of appetite, and metallic taste. If any bother you, consult your doctor.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol during treatment with Adlinameg 2.5/850mg Tablet due to the increased risk of undesired effects. 


Pregnancy
CONSULT YOUR DOCTOR

Adlinameg 2.5/850mg Tablet is not recommended for use during pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine. 


Breastfeeding
CONSULT YOUR DOCTOR

Adlinameg 2.5/850mg Tablet is not recommended for use during pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine. 


Driving
CAUTION

Drive only when physically stable and mentally alert. If you feel drowsy after taking these medications, avoid driving or operating machinery. Your safety and the safety of others are paramount.


Kidney
CONSULT YOUR DOCTOR

Adlinameg 2.5/850mg Tablet is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.


Liver
CONSULT YOUR DOCTOR

Adlinameg 2.5/850mg Tablet is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gallstones. Therefore, consult your doctor before taking it.

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✔️ Uses of Adlinameg 2.5/850mg Tablet
  • Type 2 Diabetes Mellitus
✔️ How does Adlinameg 2.5/850mg Tablet work?

Adlinameg 2.5/850mg Tablet is a combination of two active ingredients: Metformin and Linagliptin. Metformin improves the body's sensitivity to insulin, helping to regulate blood sugar levels, and reduces the liver's production of sugar. Linagliptin, on the other hand, enhances insulin release from the pancreas and boosts the activity of a hormone called Glucagon-like peptide-1, which aids in controlling blood sugar levels. This combination medication is used to manage and regulate blood sugar in individuals with type 2 diabetes.

✔️ Side Effects of Adlinameg 2.5/850mg Tablet

Common side effects of Adlinameg 2.5/850mg Tablet may include nausea, diarrhea, stomach pain, and changes in taste like a metallic taste. Uncommon effects could involve inflamed nose or throat, cough, constipation, loss of appetite, vomiting, and skin itchiness. Rare side effects that warrant immediate medical attention include:

  1. Signs of severe low blood sugar: Increased sweating, shakiness, anxiety, blurred vision, tingling lips, pale skin, mood changes, or confusion.
  2. Serious allergic reaction: Hives, swelling of the face, lips, tongue, or throat leading to breathing or swallowing difficulties.
  3. Severe skin rashes with redness and blistering.
  4. Signs of lactic acidosis: Cold hands or feet, dizziness, irregular heartbeat, weakness, muscle pain, trouble breathing, sleepiness, stomach pains, nausea, or vomiting.
  5. Signs of liver damage: Tiredness, loss of appetite, weight loss, with or without yellowing of the skin or eyes.
  6. Inflammation of the pancreas: Severe stomach pain radiating to the back, along with nausea and vomiting.

If you experience any of these rare side effects, stop taking the medication and consult your doctor immediately.

✔️ Quick Suggestions:
  • Divide your plate into halves, with one half filled with starchy vegetables, one quarter with proteins, and the remaining quarter with whole grains.
  • Eat at regular intervals and avoid long gaps between meals or snacks.
  • Keep track of your blood sugar levels regularly, especially when you experience fluctuations.
  • Engage in at least 150 minutes of moderate-intensity exercise or 75 minutes of high-intensity exercise each week.
  • Replace refined carbohydrates with whole-grain foods and increase your intake of fruits, vegetables, and fiber-rich foods.
  • Reduce saturated fat intake by avoiding foods like chips, pastries, and biscuits. Opt for oils containing omega-3 fatty acids for daily cooking.
  • Take Metformin + Linagliptin with food to minimize the risk of stomach upset. Use it alongside exercise and a healthy diet to manage blood sugar levels.
  • Carry a source of sugar for immediate relief in case of low blood sugar when using this medication with other antidiabetic drugs or alcohol.
  • Regularly monitor your blood sugar levels while taking the medication.
  • Inform your doctor about your diabetes treatment if you're scheduled for surgery under general anesthesia.
  • Lactic Acidosis Awareness: Seek medical attention if you experience deep or rapid breathing, persistent nausea, vomiting, or stomach pain, as this could be a sign of lactic acidosis.
  • Practice stress management techniques like mindfulness to control stress-related changes in blood sugar.
  • Opt for low-fat dairy products like yogurt, milk, and cheese.
  • Maintain normal blood pressure (140/90) to reduce the risk of cardiovascular diseases associated with diabetes.
✔️ Indication

Adlinameg is prescribed to adult patients with type 2 diabetes mellitus to enhance glycemic control. It serves as an additional treatment alongside diet and exercise in cases where patients are not effectively managed with their maximum tolerated dose of metformin alone. It is also utilized in patients already receiving a combination of linagliptin and metformin.

Furthermore, Adlinameg is indicated as part of triple combination therapy. When used with sulphonylurea, it complements diet and exercise for adult patients whose metformin and sulphonylurea treatment does not suffice for proper glycemic control. Similarly, when combined with insulin, it helps improve glycemic control for adults whose current regimen of insulin and metformin is insufficient.

✔️ Pharmacology

Linagliptin aids individuals with type 2 diabetes in controlling blood sugar levels. By inhibiting the enzyme DPP-4 (dipeptidyl peptidase-4), it prevents the degradation of incretin hormones like GLP-1 and GIP. This action prompts insulin release from pancreatic beta cells while decreasing glucagon production by pancreatic alpha cells. The result is increased active incretin hormone levels, which help regulate blood sugar.

Metformin Hydrochloride belongs to the biguanide class and acts as an antihyperglycemic medication for type 2 diabetes. It reduces both baseline and postprandial blood glucose levels. Unlike sulfonylureas, it doesn't cause hypoglycemia. Metformin works by decreasing hepatic glucose synthesis, absorption of glucose in the intestines, and enhancing insulin sensitivity, ultimately improving peripheral glucose uptake and utilization.

✔️ Dosage & Administration of

Linagliptin & Metformin tablet: Dosage varies based on effectiveness and tolerance. Max recommended dose is 2.5mg Linagliptin + 1000mg Metformin twice daily with meals. Start with 2.5mg Linagliptin + 500mg Metformin if not on Metformin. Adjust the dose if already on Metformin or Linagliptin. Components can be switched to this combo.

Linagliptin & Metformin extended-release tablet: Dosage varies based on effectiveness and tolerance. Max recommended dose is 5mg Linagliptin + 2000mg Metformin once daily with a meal. Start with 5mg Linagliptin + 1000mg Metformin if not on Metformin. Adjust the dose if already on Metformin or Linagliptin. Switch from immediate release to extended release with the same Linagliptin dose and similar Metformin dose.

✔️ Interaction

When taking multiple medications or combining them with specific foods or beverages, there's a risk of drug interactions. Here are some important interactions and precautions to consider while using Adlinameg 2.5/850mg Tablet:

Interaction with Alcohol: Avoid alcohol consumption while taking this medication. If you experience symptoms like prolonged weakness, muscle pain, sleeplessness, or breathing difficulties after alcohol intake, inform your doctor immediately. Alcohol use can increase the risk of lactic acidosis, so it's best to limit or avoid its consumption.

Interaction with Other Medications:

  • Decreased Effect: Certain drugs that may lead to increased blood sugar levels (hyperglycemia) such as diuretics, corticosteroids, thyroid products, and more, can reduce the effectiveness of Adlinameg 2.5/850mg Tablet. They might compromise glycemic control.
  • Increased Effect: Furosemide can increase metformin levels in the blood. Certain cationic drugs eliminated by the kidneys (e.g., digoxin, quinidine, etc.) can interact with metformin and potentially lead to increased toxicity.

Interaction with Medical Conditions:

  • Lactic Acidosis: Inform your doctor about kidney impairment, heart disease, severe diarrhea, and septicemia before taking Adlinameg 2.5/850mg Tablet. Close monitoring of blood sugar levels and supervised dosing might be necessary.
  • Vitamin Deficiency: Let your doctor know about any history of anemia or vitamin deficiencies, especially Vitamin B12 and folic acid, as the medication might affect their absorption.

Interaction with Food:

  • Food: Taking the medication with food can help reduce gastrointestinal upset. Food intake can slightly decrease the extent and delay the absorption of the medication.
  • Glucose: The medication decreases blood glucose concentration. Hypoglycemia may occur if a patient is predisposed. Monitor blood glucose levels, especially in cases of reduced caloric intake, strenuous exercise, alcohol consumption, or when combined with other oral antidiabetic agents.
  • Vitamins: The medication can impact the absorption of Vitamin B12 and folic acid. Monitor for signs of deficiency and discuss potential supplements with your doctor.

Being aware of these interactions and precautions can help you use Adlinameg 2.5/850mg Tablet safely and effectively. Always consult your doctor before making any changes to your medication regimen.

✔️ Contraindications

Avoid using this medicine if:

  • You have a known allergy to linagliptin, metformin, or any other ingredients in the medication.
  • You have type 1 diabetes mellitus.
  • You are undergoing treatment for diabetic ketoacidosis.
  • You have pre-existing medical conditions such as kidney or liver impairment, pancreas disorder, or any other serious health issues.
✔️ Pregnancy & Lactation

This medication should be used with caution during pregnancy and while breastfeeding. As there are no sufficient and well-controlled trials in pregnant women with this combination or its separate components, it should only be taken if clearly necessary during pregnancy. If given to a nursing woman, extreme caution should also be exercised. It's important to discuss the potential risks and benefits with your healthcare provider before taking this medication if you are pregnant or breastfeeding. Your doctor will help you make an informed decision based on your individual circumstances.

✔️ Precautions & Warnings
  • Ensure you do not have pre-existing medical conditions such as liver or kidney issues, pancreas disorders, or Type 1 diabetes.
  • Avoid concurrent use with other anti-diabetic medications. Exercise caution if you have heart problems like irregular heartbeat or heart failure.
  • Be vigilant for symptoms of lactic acidosis, such as vomiting, stomach pain, muscle cramps, fatigue, and difficulty breathing.
  • Monitor for symptoms of dehydration, vomiting, diarrhea, and fever.
  • Note that this medication is not recommended for patients under 18 years old, and extra care is needed when administering it to the elderly, especially those above 80 years of age.
✔️ Storage Conditions
  • Store in a cool and dry place, below 30°C.
  • Keep it away from children and pets in the original package.
  • Avoid using expired medicines.
Frequently Asked Questions (FAQ)

Metformin+Linagliptin generally doesn't cause hypoglycemia (low blood sugar) alone, but it may occur if you don't consume enough calories. Signs include nausea, headache, hunger, sweating, dizziness, fast heart rate, and feeling shaky. This is more likely if you miss meals, drink alcohol, over-exercise, or take other antidiabetic meds. Monitor blood sugar regularly and keep glucose tablets, honey, or juice handy.

Take Adlinameg 2.5/850mg Tablet preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Taking a higher dose of Adlinameg 2.5/850mg Tablet isn't effective and can cause toxicity. Stick to the prescribed dose. If it's not working, consult your doctor for adjustments or alternatives.

Consult your doctor before taking Adlinameg 2.5/850mg Tablet with insulin due to higher risk of hypoglycemia (low blood sugar).

Constipation is a common side effect of Adlinameg 2.5/850mg Tablet. Increase fiber intake, stay hydrated, and exercise regularly. If the issue persists, consult your doctor.

No, Adlinameg 2.5/850mg Tablet is only prescribed to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.'

Exercise caution when prescribing Adlinameg 2.5/850mg Tablet to older adults due to a higher risk of hypoglycemia. Adjust doses as needed and adhere to the prescribed regimen.
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Check our pricing section for Adlinameg 2.5/850mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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